Welcome to 13562 Lake Mary Jane Rd, an extraordinary lakeview estate in the highly desirable Isles of Pine communityjust minutes from the heart of Lake Nona. Set along the pristine shores of Lake Mary Jane, one of Central Floridas most coveted and seaplane accessible lakes, this location offers a rare blend of peaceful, nature filled surroundings and easy access to everything Orlando has to offer. Known for its low boat traffic, incredible fishing, and glassy morning water perfect for skiing or paddleboarding, Lake Mary Jane is a hidden gem for those seeking both adventure and serenity. This completely reimagined home offers almost 4,000 square feet of custom living space, blending privacy, luxury, and design in one unforgettable property. The primary suite is downstairs, featuring a spa style bath with a glass enclosed dual head shower, freestanding tub, dual vanities, and custom built ins. Youll also find a flexible lounge or office space on the main level, along with a jaw dropping brick wood burning fireplace, custom wood wrapped mantle, wood beam ceilings, and a bright, open living space with oversized sliders and picture windows showcasing sweeping lake views. The kitchen is a true centerpiece with a massive island (cabinetry on both sides), quartz countertops, Viking gas range, Caf appliances, and designer lighting. Upstairs features a spacious loft, private upper deck with birds eye lake views, three guest bedrooms (all with custom closets), and a beautifully appointed guest bath. Extensive updates include: new roof, new windows, updated plumbing and electrical, 2 new A/C units, dual water heaters, well and irrigation upgrades, custom interior/exterior lighting, crown accents, custom closets, and fresh paint on the home and fencing. Exterior features include a solar powered fence, deck lighting, and uplighting to enhance both ambiance and security. A 3 car garage and proximity to the community boat ramp (just blocks away) complete the package. Luxury. Lakefront. Lifestyle. A rare find like this doesnt come around often! Reach out to secure your showing today.